Developed by Ray Sahelian, M.D. and Passion Rx with maca, a potent sexual enhancer
Maca herb information Maca Studies and Maca Review
Maca (Lepidium meyenii) is a root-like vegetable
shaped like a radish. It grows in the harsh climate of the Andes Mountains in
South America at elevations from 11,000 to
up to 15,000 feet. Maca is traditionally used in the Andean region for its
supposed aphrodisiac and fertility-enhancing properties.
Maca Supplement Facts - Highest QualityWhat Maca extract research
says
In one study, researchers fed high dosages of maca extracts to male
mice. As a result, the
frequency with which they coupled with female mice
tripled. In rats with erectile
dysfunction, the time needed between successive
couplings was reduced by half.
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New Maca Research
The in vitro biological activity of Lepidium meyenii maca extracts.
Cell Biol Toxicol. 2006 Mar;22(2):91-9.
Valentova K, Buckiova D, Kren V, Peknicova J, Ulrichova J, Simanek V.
Institute of Medical Chemistry and Biochemistry, Faculty of Medicine, Palacky
University, Olomouc.
The biological activity of methanolic and aqueous extracts from dehydrated
hypocotyls of Lepidium meyenii (Brassicaceae, vernacular name maca ), was
studied on rat hepatocytes and human breast cancer MCF-7 cells. The maca
extracts did not exhibit cytotoxicity in hepatocyte primary cultures up to 10
mg/ml as measured by the MTT viability test, and lactate dehydrogenase (LDH) and
aspartate aminotransferase (AST) leakage. Moreover, after 72 h, extracts
inhibited LDH and AST leakage from the hepatocytes. When hepatocytes were
intoxicated by t-butyl hydroperoxide, neither extract prevented oxidative
damage. Both maca extracts showed weak antioxidant activity in the DPPH radical
scavenging test with IC(50) values of 3.46 +/- 0.16 and 0.71 +/- 0.10 mg/ml, for
aqueous and methanolic extracts, respectively. Thus, the observed effect on
spontaneous enzyme leakage is probably mediated through mechanisms other than
antioxidant activity. Both methanolic and aqueous maca extracts have shown
estrogenic activity comparable with that of silymarin in MCF-7 cell line. Maca
estrogenicity was exhibited in the range from 100 to 200 mug of extract per ml.
The findings in the present study show that maca does not display in vitro
hepatotoxicity. In contrast, a slight cytoprotective effect, probably not
mediated by antioxidant capacity, was noted. Maca extracts exhibited estrogenic
activity comparably to the effect of silymarin in MCF-7 cells.
Maca reversed the
lead acetate induced-Damage on reproductive function in male rats.
Food Chem Toxicol. 2006 Feb 27;
Rubio J, Riqueros MI, Gasco M, Yucra S, Miranda S, Gonzales GF.
Department of Biological and Physiological Sciences, Faculty of Sciences and
Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru; Instituto de
Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Lima, Peru
Rats were treated with 0, 8, 16 and 24mg/kg of lead acetate (LA) (i.p.) for 35
days with or without Maca. Maca was co-administrated orally from day 18 to day
35. The lengths of stages of the seminiferous epithelium were assessed by
transillumination. Also, sex organ weights, testicular and epididymal sperm
count, sperm motility, daily sperm production, sperm transit rate and serum
testosterone levels were measured. Lead acetate treatment resulted in a
dose-response reduction of lengths of stages VIII and IX-XI, and serum
testosterone levels. However, rats treated with 8 and 16mg/kg but not 24mg/kg of
lead acetate showed a low number of testicular spermatids, low daily sperm
production (DSP) and low epididymal sperm count. Administration of Maca to rats
treated with lead acetate resulted in higher lengths of stages VIII and IX-XI
with respect to lead acetate-treated rats. Moreover, treatment with Maca to lead
acetate-treated rats resulted in lengths of stages VIII and IX-XI similar to the
control group. Maca administration also reduced the deleterious effect on DSP
caused by lead acetate treatment. Maca prevented LA-induced spermatogenic
disruption in rats and it may become in a potential treatment of male
infertility associated with lead exposure.
Effect of ethanol extract of Lepidium
meyenii Walp. on osteoporosis in ovariectomized rat.
J Ethnopharmacol. 2006 Apr 21;105(1-2):274-9. Zhang Y, Yu L, Ao M, Jin W.
School of Life Science & Technology, Huazhong University of Science &
Technology, 430074 Wuhan, PR China.
Maca is a cruciferous plant from the Andes of Peru. The
root of Maca is traditionally employed for its supposed properties in
aphrodisiacs and improving fertility, it also has been widely used to help
alleviate the symptoms of menopause. The purpose of this study was to evaluate
the effect of ethanol extract of Maca on postmenopausal osteoporosis in
ovariectomized rats. Female Sprague-Dawley rats were divided into four groups:
Sham-operated and ovariectomized groups were fed with equivolume of distilled
water, and the remaining ovariectomized groups were orally administrated with
ethanol extract of Maca at 0.096 and 0.24g/kg for 28 weeks. The findings derived
from the basis of bone mineral density, biomechanical, biochemical and
histopathological parameters indicated that higher dose of ethanol extract of
Maca was effective in the prevention of estrogen deficient bone loss.
Maca herb emails
Q. I've been taking maca powder every day and on some occasions every second day
and feel an incredible difference in my wellbeing as a result of this. However,
I have a cough which has come and gone over the past years and often persists
for months at a time. I can not remember if I got the cough this time before I
started talking maca or after but I have noticed that I start to develop more
phlegm after taking maca herb which becomes extremely irritating. I know that
phlegm it's self is protein based and that maca has a high degree of absorbable
protein and so I thought there may be some connection there. I only take half a
tea spoon in hot water at a time when taking maca but I still feel the effects
of plegm being produced after each time. I do not want to stop taking maca
because I feel so great when I take it but at the same time this cough is
driving me crazy. Do you think the way I am taking maca or the quantity that I'm
taking is affiliated with this problem?
A. Even though phlegm is protein based, it would not have anything
to do with protein in maca since people can eat chicken with protein and yet not
have phlegm. We have not heard of maca causing phlegm or couth, but then again
we don't know many people who have taken maca for prolonged periods. It is
always a good idea if a side effect is being suspected from an herb to take a
break from it. There are many herbs that have overlapping functions and effects.
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