Ketogenic diet food
The ketogenic diet is very high in fats and low in carbohydrates. The ketogenic was first developed more than 80 years ago. It makes the body burn fat for energy instead of glucose. A ketogenic diet seizure is used to reduce the incidence of seizure. For general information on a healthy diet.
ketogenic diet epilepsy research
Anticonvulsant mechanisms of the ketogenic diet.
Epilepsia. 2007 Jan;48(1):43-58. Bough KJ, Rho JM.Center for Drug Evaluation
& Research, Food and Drug Administration, Rockville, Maryland.
The ketogenic diet is a broadly effective treatment for medically refractory
epilepsy. Despite nearly a century of use, the mechanisms underlying its
clinical efficacy remain unknown. In this review, we present one intersecting
view of how the ketogenic diet may exert its anticonvulsant activity against the
backdrop of several seemingly disparate mechanistic theories. We summarize key
insights gleaned from experimental and clinical studies of the ketogenic diet,
and focus particular attention on the role that ketone bodies, fatty acids, and
limited glucose may play in seizure control. Chronic ketosis is anticipated to
modify the tricarboxcylic acid cycle to increase GABA synthesis in brain, limit
reactive oxygen species (ROS) generation, and boost energy production in brain
tissue. Among several direct neuro-inhibitory actions, polyunsaturated fatty
acids increased after ketogenic diet induce the expression of neuronal
uncoupling proteins, a collective up-regulation of numerous energy metabolism
genes, and mitochondrial biogenesis. These effects further limit ROS generation
and increase energy production. As a result of limited glucose and enhanced
oxidative phosphorylation, reduced glycolytic flux is hypothesized to activate
metabolic K(ATP) channels and hyperpolarize neurons and/or glia. Although it is
unlikely that a single mechanism, however well substantiated, will explain all
of the diet's clinical benefits, these diverse, coordinated changes seem poised
to stabilize synaptic function and increase the resistance to seizures
throughout the brain.
Diet questions
Q. What herbs helps one eat less?
A. We have not seen human research thus far regarding
pomegranate supplements for weight loss. Herbs that could reduce appetite
include green tea extract
and hoodia. You can
purchase
Green Tea Extract and
Hoodia Extract here.
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