The hoodia plant is a spiny succulent (similar to a cactus) that grows in the
Kalahari desert in Africa, mostly in the arid areas of South Africa, Botswana, and Namibia.
San Bushmen (who are one of the world's oldest and most primitive
hunter-gatherer tribes), have known about the hoodia plant for countless generations. Rock paintings of the San Bushmen
go back more than 20,000 years. The nomadic Bushmen, who live in this harsh and
arid desert, use the hoodia gordonii plant as an appetite suppressant during
their long marches and hunting trips through the vast desert. As of September
2007, I am not aware of any human studies published with hoodia gordonii
supplements for weight loss. Below I mention one rodent study that I came across
that showed hoodia was able to reduce appetite.
For a highly effective product
with hoodia gordonii extract that helps you eat less, see
Diet-Rx Natural Appetite Suppressant with
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Hoodia diet pill for obesity
Hoodia diet pills are effective for
appetite control in most, but not all, users. We've
had feedback from hoodia diet pill
users regarding appetite control, and the results are mixed. Overall, though, it
seems about 60% of the feedback has been positive.
Hoodia Diet Pill 400
mg,
Hoodia Gordonii extract 20:1
Note:
This hoodia diet pill is a 20:1 extract which means it
is 20 times as concentrated as regular hoodia cactus. 400 mg of Hoodia extract equals about
8,000 mg or 8 grams of the actual plant.
Hoodia gordonii is a succulent found in the Kalahari Desert of South Africa. The
San Tribesmen of the Kalahari have been using hoodia as a food source for
thousands of years.
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Hoodia Gordonii
Supplement Facts
Hoodia gordonii Stem Extract (20:1) - 400 mg *
Suggested Use: 1 or 2 hoodia diet pill capsules in the morning before breakfast on an empty
stomach.
* Hoodia daily value not established.
Hoodia powder versus Hoodia extract
Which form of hoodia
gordonii is better? We really don't
know the answer to
whether hoodia powder or hoodia extract is better since no studies have been
done comparing the two.
Appetite control and Hoodia diet pill Research
It was in the 1960s that scientists first discovered that when rodents were
given hoodia
gordonii, they practically stopped eating.
According to
news reports, researchers
in South Africa discovered hoodia gordonii contains a previously unknown
compound, not known to be present in other plants, which has since been named P 57. Apparently the license was sold to a British pharmaceutical company, Phytopharm, who in turn sold the development and marketing rights to Pfizer
Corporation. Studies with hoodia gordonii are being conducted at this time. A preliminary
report in the news media which I can't find in medical journals indicates that hoodia gordonii is able to suppress appetite in humans.
Here is a recent study with hoodia gordonii done with rats.
An appetite suppressant from Hoodia species.
Phytochemistry. 2007 Jun 29; van Heerden FR, Marthinus Horak R, Maharaj VJ,
Vleggaar R, Senabe JV, Gunning PJ.
School of Chemistry, University of KwaZulu-Natal, Private Bag X01, Scottsville
3209, South Africa.
Two pregnane glycosides were isolated by fractionation of the dried stems of
Hoodia gordonii. Compound 1 was tested for its appetite suppressant properties
in rats by oral gavage at 6.25-50mg/kg and the results showed that all doses
resulted in a decrease of food consumption over an eight day period and a body
mass decrease when compared to the control sample receiving only the vehicle.
Is Hoodia a diet pill?
We're still trying to evaluate the feedback from users of hoodia diet
pills
Thus far we tend to lean towards the possibility that hoodia
gordonii
is in fact helpful
to curb appetite, but we still need many more case reports from hoodia users
before coming to a firmer opinion. For more
hoodia information.
Hoodia diet pill Side Effects
Thus far there have not been any reports in the medical literature
regarding hoodia diet pill side effects. We have talked to a number of people who have
taken this plant, and none reported any significant hoodia side effects. However, the
longest any of them had taken hoodia gordonii was 3 weeks. Therefore, we don't
know if hoodia has side effects if taken for prolonged periods. The San Bushmen
consume hoodia gordonii on a regular basis and it appears that they are healthy
although we don't know how often they eat the hoodia fruit. Plus, most hoodia
gordonii
users
in this country are taking the hoodia extract and not the whole hoodia cactus
fruit. As more people take this popular supplement, it is quite likely that more
hoodia diet pill side effects will surface.
Chemical composition of hoodia
gordonii
Hoodia has many components, including C21-steroidal derivatives, namely
gordonosides, along with goodigosides, and oxypregnane glycosides. P57AS3 (P57),
an oxypregnane steroidal glycoside, is believed to be the active constituent
from this plant in terms of appetite suppression. P57 increases the content of
ATP by 50-150% in hypothalamic neurons which may be one of the mechanisms by
which hoodia works as an appetite suppression.
Hoodia diet pill Research Update
Determination of the appetite suppressant P57 in Hoodia gordonii plant
extracts and dietary supplements by liquid chromatography/electrospray
ionization mass spectrometry (LC-MSD-TOF) and LC-UV methods.
J AOAC Int. 2006 May-Jun;89(3):606-11. Avula B, Wang YH, Pawar RS, Shukla YJ,
Schaneberg B, Khan IA.
National Center for Natural Products Research, Research Institute of
Pharmaceutical Sciences, The University of Mississippi, MS 38677, USA.
Hoodia gordonii is traditionally used in South Africa for its appetite
suppressant properties. P57AS3 (P57), an oxypregnane steroidal glycoside, is the
only reported active constituent from this plant as an appetite suppressant.
Effective quality control of these extracts or products requires rapid methods
to determine P57 content. New methods of liquid chromatography/mass spectrometry
(LC/MS) and LC-UV for analysis of P57 from Hoodia gordonii have been developed.
The quantitative determination of P57 was achieved with a Phenomenex Gemini
(Torrance, CA) reversed-phase column using gradient mobile phase of water and
acetonitrile, both containing 0.1% acetic acid. The method was validated for
linearity, repeatability, and limits of detection and quantification. Good
results were obtained in terms of repeatability (relative standard deviation
<5.0%) and recovery (98.5-103.5%). The developed methods were applied to the
determination of P57 for Hoodia gordonii plant samples, one related genus (Opuntia
ficus-indica), and dietary supplements that claim to contain Hoodia gordonii.
Hoodia diet pill emails
Q. I'm a 360 lbs white male, age 40. I took pure hoodia diet pills, 2 a day, for a
week and did not notice any effect on appetite or weight loss. I'm not convinced
hoodia is a diet pill.
Q. Is hoodia a diet pill ?
A. With time it is becoming more convincing that hoodia is an
effective diet pill, at least in the short term. Whether taking a hoodia diet
pill
supplements leads to long term weight loss is still not clear.
Q. How do I know if I buy a hoodia diet pill product that
it is pure hoodia?
A. Unfortunately, we would not be surprised if some
companies are selling hoodia diet pill products that are not true to their label. Buy
hoodia a diet pill from a company you are familiar with.
Q. I was interested in beginning to take hoodia diet pill
for appetite
suppression. However, I am currently taking 10 mg of Enalapril for treatment of
high blood pressure. Will hoodia diet pill and these pills interact?
A. No human trials are available regarding hoodia diet pill
supplement use, therefore it is very difficult to say what kind of interaction,
if any, would occur when taking a hoodia diet pill and a blood pressure medication such as
an ACE inhibitor.
Q. I would like to try a hoodia diet pill but
there are literally dozens of products marketed on the internet. How do I know
that there is actual hoodia gordonii in these pills?
A. Unless you send the product to an independent lab, you can not
be 100 percent certain that the product you buy will have hoodia gordonii or the
right amount as stated on the label. However, most of the large companies
selling hoodia weight loss pills are reliable.
Jiaogulan Chinese
herb is popular in Asia
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